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Recipes / Keto Cheeseburger Casserole

Filed Under: Recipes

Keto Cheeseburger Casserole

November 4, 2025 by el hassan Leave a Comment

This Keto Cheeseburger Casserole has all the delicious flavor of a classic cheeseburger—without the bun or the carbs! It’s hearty, cheesy, and incredibly satisfying, making it a perfect low-carb comfort food dinner that the whole family will love.

Why You’ll Love It

Casseroles are the ultimate weeknight solution—just mix, bake, and dinner’s ready! This one is no exception. It’s creamy, flavorful, and quick to make, coming together in just about 30 minutes. Plus, it’s flexible—feel free to mix in extra veggies like cauliflower rice or spinach for a complete one-dish meal.


Ingredients You’ll Need

(Find full measurements in the printable recipe card below.)

  • Ground Beef: I like to use extra-lean (93%) for less grease, but 85% lean also works great.
  • Onion & Garlic: Fresh gives the best flavor, but you can substitute with 2 teaspoons each of onion and garlic powder if you’re short on time.
  • Mayonnaise: Adds rich creaminess. Try sriracha mayo for a spicy kick!
  • Mustard: Dijon or yellow both taste great here.
  • Cheddar Cheese: Sharp or extra-sharp cheddar gives that perfect cheeseburger tang.

Optional Add-Ins & Variations

  • Bacon: Add cooked crumbled bacon for extra smoky flavor.
  • Ground Chicken or Turkey: A leaner but still delicious option.
  • Spices: Smoked paprika or chili powder add a deeper, richer taste.
  • Jalapeños: For a little heat, mix in some pickled jalapeño slices before baking.
  • Veggies: Stir in riced cauliflower or a handful of spinach for added nutrition.

How to Make Keto Cheeseburger Casserole

  1. Prep: Preheat oven to 400°F and lightly grease a 2-quart baking dish with olive oil spray.
  2. Cook the Beef: In a large skillet, heat olive oil over medium-high heat. Add the beef and onions. Cook until the beef is browned and onions are tender, about 5 minutes.
  3. Season: Drain excess fat if needed. Stir in salt, pepper, and garlic. Cook for another minute.
  4. Add the Sauce: Turn off the heat. Stir in mayonnaise, unsweetened ketchup, mustard, and 1 cup of cheddar cheese until everything’s creamy and well combined.
  5. Bake: Transfer the mixture to your baking dish and sprinkle with the remaining cheese.
  6. Finish: Bake for about 15 minutes, until the cheese is melted and bubbly. (Or broil for 1–2 minutes if you prefer a golden top.)

Tips for Success

  • Drain excess grease before baking for the best texture.
  • For a full meal, mix in 1–2 cups of cauliflower rice or baby spinach before baking.
  • Store leftovers in an airtight container for up to 4 days. Reheat gently in the microwave or oven.
  • Freeze individual portions for up to 3 months for an easy low-carb meal anytime!

Serving Suggestions

This rich, cheesy casserole pairs beautifully with lighter sides like:

  • Roasted asparagus or broccoli
  • Arugula or coleslaw
  • Sautéed spinach
  • Roasted mini peppers

Nutrition (Per Serving)

Calories: 458 | Carbs: 4g | Protein: 38g | Fat: 31g | Sugar: 2g | Sodium: 771mg


Final Thoughts

This Easy Keto Cheeseburger Casserole delivers big cheeseburger flavor in a simple, low-carb bake. It’s quick enough for busy nights but delicious enough to feel special. Whether you’re following keto or just craving something comforting and cheesy, this recipe is a definite keeper

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